In his search for the Lightbringer, Dracula crosses paths with a beautiful crusader named Alina who bears a remarkable resemblance to his murdered bride. One look at her and Dracula is immediately smitten. Could Alina be the reincarnation of his long-dead love? Dracula has Alina kidnapped and brought to his castle where the Beast must now try to win his Beauty's heart.

Cancer-terminal tycoon Peter Murdoch's secret Wexel Hall Pharmaceuticals lab has developed a blood orchid extract cure. To examine why it works optimally in snakes, they also bread a super-anaconda strain. But the original pair escapes, leaving a bloody trail of corpses. Murdoch runs, instructing his staff to clean up. They keep failing and being eaten like unsuspecting locals, some alive, even after enlisting ruthless big game hunter Hammett. The fast-growing pregnant monster sheds its skin, thus disabling the only tracking device.

Henry Perkins, a mild-mannered accountant, accidentally trades briefcases with another man, to find out that there's five million dollars inside. Henry tells his unsuspecting wife of their new-found fortune, but she doesn't embrace it as well as he does. Soon they're joined by their best friends, a cop on the take, a cop on the hunt, and the dreaded Mr. Big, who has come to claim his million dollars.

An intelligence operative discovers that no one is what they seem in the shadowy world of espionage.

Decades after a rock church in communist Romania's Carpathians caved when an expedition caused a landslide and buried everyone, Dr. Nicolai's scientific team exploring the associated Templar Knights monster fighting-legend discovers a deep, flooded cave system and hires the brothers Jack and Tyler's brilliant divers team to explore it. Another explosion traps them, after finding a mysterious parasite turning all species carnivore, and later an independently evolved predator species. Jack may be infected and turning, but Tyler sticks with him, so the group splits, hunted by the monsters, which also fly.

Picking up immediately where Anaconda 3 left off, herpetologist Amanda Hayes finally learns her employer Murdoch's true colors when he hires a doctor to harvest a fresh supply of blood orchids to experiment with the regenerative nectar on a baby snake in order to seek treatment for his own terminal illness. Amanda is forced to secretly bring together another team of scientists whom face off against a heavily armed squad of Murdoch's men to steal the coveted orchids before the killer Anaconda hunts both parties down.

1938, Romania: at 70, a professor of language and philosophy, Dominic Matei, contemplates suicide: the love of his life is dead, and he remains unable to complete his life's work on the origins of language. Then, he's struck by lightning. After a slow recovery, he grows younger. He must now avoid Nazis, who want to study and experiment on him. Some years later, he meets a young woman who has her own passage through a lightning storm. Not only does Dominic find love again, but her new abilities hold the key to his research. Is the sweetness of life finally at hand?